To content
Faculty of Biochemical and Chemical engineering

MSc Christina Schmidt

Mail: Christina Schmidt

Chair Technical Biochemistry

Emil-Figge-Str. 66, Room G1-6.20

44227 Dortmund

Phone: +49 231 755 5475

Christina Schmidt © Tu Dortmund

Field or research

Biotechnological production of cannabinoids in Saccharomyces cerevisiae

Cannabinoids are derived from the secondary metabolism of the plant Cannabis sativa. The biotechnological production of cannabinoids in a microbial host organism is a promising alternative for conventional production methods. In order to produce cannabinoids in a biotechnological process using a microbial host organism the enzymatic steps have to be integrated, analyzed and improved. This project focuses on the development and optimization of a whole cell process for the production of cannabinoids from simple carbon sources in S. cerevisiae.


Schmidt, C., Aras, M., and Kayser, O. Engineering cannbinoid production in Saccharomyces cerevisiae. Biotechnol J. 2024,

Jordan, E.N., Schmidt, C. and Kayser, O. Foldseek reveals a CBGA prenylating enzyme GlyMa_02G168000 from Glycine max. Biochem Biophys Res Commun 2024, DOI:

Thomas, F., Schmidt, C., and Kayser, O. Bioengineering studies and pathway modeling of the heterologous biosynthesis of tetrahydrocannabinolic acid in yeast. Appl Microbiol Biotechnol 2020, DOI: 10.1007/s00253-020-10798-3.

Supervised theses