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Faculty of Biochemical and Chemical engineering

Lectures

Sommersemester

Bachelor

The biosynthesis of biomolecules such as nucleic acids, proteins and fatty acids, as well as linear and cyclic metabolic pathways, including the citric acid cycle, glycolysis, mevalonate pathway, shikimate pathway, photosynthesis, steroid biosynthesis are taught.

The content focus is on signal transduction and cellular functions, including proteins as tools, principles of intra- and intercellular communication such as hormonal control of complex systems.

The module introduces the use of the English language through case studies of science and technology communications from the fields of bioengineering and chemical engineering; case studies include written documents/publications written in English and authentic audio examples of popular scientific design on topics from the two engineering disciplines. The focus of the exercise is on the use of the English language as students paraphrase and comment on provided publications from the daily press or magazines (e.g. Times , Scientific American, etc.) as well as from professional organs in English in written or oral form. In addition, an independently prepared (group or individual) presentation will be presented.

Introduction, definition of pharmaceutical biotechnology, basic operations, working techniques for recombinant pharmaceutical proteins, cultivation techniques for producers, GMP production, pharmaceutical bioanalytics, vaccines, somatic gene therapy, transgenesis, pharmaceutical information, patenting, drug approval.

Master

Introduction, definition of pharmaceutical biotechnology, basic operations, working techniques for recombinant pharmaceutical proteins, cultivation techniques for producers, GMP production, pharmaceutical bioanalytics, vaccines, somatic gene therapy, transgenesis, pharmaceutical information, patenting, drug approval.

The execution of large theses such as the master's thesis requires not only scientific aptitude but also an examination of questions concerning structure, design and content. Students are expected to have a high level of learned competence in order to plan and carry out a long scientific work in the laboratory and to record results. The subsequent theoretical processing, analysis and evaluation requires a skillful handling of the current literature and the use of databases. The goal of the course is to introduce students to scientific work, with particular attention to aspects of the philosophy of science, personal self-knowledge of science, and philo- sophic embedding. Furthermore, methods for stress reduction (yoga, meditation) will be introduced, time planning as well as dealing with complex workflows will be analyzed, and communication within the team and dealing with failure and unexpected results will be discussed.

The lecture "Introduction to Protein Chemistry" deepens the understanding of proteins. Biosynthesis and structure formation as well as the detection and modification possibilities of post-translational protein modifications (disulfide bridges, glycosylation) are discussed. Bioinformatic tools are presented with which proteins can be characterized and visualized in silico. This will be tried out by the students themselves on examples in the computer pool. In the practical part of the course, the students are expected to independently create a working procedure for the enzyme kinetic characterization of an enzyme and then apply it in practice.