MSc Christina Schmidt
E-Mail: Christina Schmidt
Lehrstuhl Technische Biochemie
Emil-Figge-Str. 66, Raum G1-6.20
44227 Dortmund
Tel.: +49 231 755 5475
Field or research
Biotechnological production of cannabinoids in Saccharomyces cerevisiae
Cannabinoids are derived from the secondary metabolism of the plant Cannabis sativa. The biotechnological production of cannabinoids in a microbial host organism is a promising alternative for conventional production methods. In order to produce cannabinoids in a biotechnological process using a microbial host organism the enzymatic steps have to be integrated, analyzed and improved. This project focuses on the development and optimization of a whole cell process for the production of cannabinoids from simple carbon sources in S. cerevisiae.
Veröffentlichungen
Schmidt, C., Aras, M., and Kayser, O. Engineering cannbinoid production in Saccharomyces cerevisiae. Biotechnol J. 2024, https://doi.org/10.1002/biote.202300507
Jordan, E.N., Schmidt, C. and Kayser, O. Foldseek reveals a CBGA prenylating enzyme GlyMa_02G168000 from Glycine max. Biochem Biophys Res Commun 2024, DOI: https://doi.org/10.1016/j.bbrc.2024.149471
Thomas, F., Schmidt, C., and Kayser, O. Bioengineering studies and pathway modeling of the heterologous biosynthesis of tetrahydrocannabinolic acid in yeast. Appl Microbiol Biotechnol 2020, DOI: 10.1007/s00253-020-10798-3.